Sigh… this pregnancy is so COMPLETELY different that my last one. Not only am I nausea all the time… I’ve got all sorts of food aversions which most of the time I don’t realize until the food is in front of me and I want to hurl… but to top it all off… my skin is in its worst condition EVER! I’ve got a rash all over my stomach… mostly concentrated according to the doctor, on my stretch marks… but it has spread to my legs… and most horrifyingly to my FACE! I want to tear the skin off everywhere! It’s so consumingly itchy!!! Trying to find some relief, I was happy to find some Calming Cream in my closet along with a bottle of Sarna… feel the cooling relief… ahhhh! It’s shortlived though… I had been using Cutivate prior to my pregnancy for the treatment of my minor excema outbreaks and was told by my OB that it was OK as a topical steroid for me to use. For some reason today… after applying just a dab on my face today, hoping for some quick remedy before the wedding we have to attend on friday afternoon… I decided to do some research on the internet… NOW I’m frightened…
Topical corticosteroids like Cutivate may cause birth defects especially when applied in large amounts. If you are or think you may be pregnant, do not use Cutivate without first checking with your doctor.
Nursing mothers should switch to bottle feed while using Cutivate.
Pregnancy Category C. Corticosteroids have been shown to be teratogenic in laboratory animals when administered systemically at relatively low dosage levels. Some corticosteroids have been shown to be teratogenic after dermal application in laboratory animals.
Systemic embr yofetal development studies were conducted in mice, rats and rabbits. Subcutaneous doses of 15, 45 and 150 µg/kg/day of fluticasone propionate were administered to pregnant female mice from gestation days 6 – 15. A teratogenic effect characteristic of corticosteroids (cleft palate) was noted after administration of 45 and 150 µg/kg/day (less than the MRHD in adults based on body surface area comparisons) in this study.
Subcutaneous doses of 10, 30 and 100 µg/kg/day of fluticasone propionate were administered to pregnant female rats in two embryofetal development studies (one study administered fluticasone propionate from gestation days 6 – 15 and the other study from gestation days 7 – 17). In the presence of maternal toxicity, fetal effects noted at 100 µg/kg/day (less than the MRHD in adults based on body surface area comparisons) included decreased fetal weights, omphalocele, cleft palate, and retarded skeletal ossification.
I can’t even go on… I don’t think I’ve used it that often during my pregnancy, but only a handful of times… but definitely during my first trimester… Normally I am ever so cautious, and with Ava’s pregnancy I didn’t touch anything prescription based other than my prenatals. Has my relaxed attitude gotten me in trouble? and I have my Ultrascreen today…